1. Madadi H, Shadmehri S. Comparison of The Effect of Two Modes Small Sided Games on The Cortisol and Testosterone levels in Soccer players. Sport Physiology & Management Investigations. 2021;13(2):29-39. [Article in Persian] [ Link] 2. Khalafi M, Symonds ME. The impact of high-intensity interval training on inflammatory markers in metabolic disorders: A meta-analysis. Scand J Med Sci Sports. 2020 Nov;30(11):2020-36. https://doi.org/10.1111/sms.13754. [ DOI] [ PubMed] 3. Syetiawinanda A, Doewes M, Purwanto B, Soetrisno S, Kristiyanto A, Pamungkasari EP. Effects of aerobic exercise and high-intensity interval training on muscle damage in an overtraining rat model. Physical Therapy Journal of Indonesia. 2025;6(1):107-13. https://doi.org/10.51559/ptji.v6i1.297. [ Link] [ DOI] 4. Norozi M, Hejazi K, Marefati H. The effect of eight weeks of high-intensity interval training combined with L-citrulline malate supplementation on muscle damage, inflammation and physical fitness factors of volleyball girls. Comparative Exercise Physiology. 2025; 21(5): 369-80. https://doi.org/10.1163/17552559-bja10048. [ Link] [ DOI] 5. Khaleghi MM, Zar A, Sadeghipour HR. Effects of small sided football and date seed (Phoenix dactylifera) powder supplementation on liver enzymes in inactive college subjects: an interventional study. J Int Soc Sports Nutr. 2025 Dec;22(1):2532686. https://doi.org/10.1080/15502783.2025.2532686. [ DOI] [ PubMed] 6. Tiller NB, Stringer WW. Exercise-induced increases in "liver function tests" in a healthy adult male: Is there a knowledge gap in primary care? J Family Med Prim Care. 2023 Jan;12(1):177-80. https://doi.org/10.4103/jfmpc.jfmpc_1923_22. [ DOI] [ PubMed] 7. Nash D, Hughes MG, Butcher L, Aicheler R, Smith P, Cullen T, et al. IL-6 signaling in acute exercise and chronic training: Potential consequences for health and athletic performance. Scand J Med Sci Sports. 2023 Jan;33(1):4-19. https://doi.org/10.1111/sms.14241. [ DOI] [ PubMed] 8. Ringleb M, Javelle F, Haunhorst S, Bloch W, Fennen L, Baumgart S, et al. Acute resistance exercise-induced changes in IL-6, IL-10, and IL-1ra in healthy adults: a systematic review and meta-analysis. MedRxiv. 2023; 23289790. https://doi.org/10.1101/2023.05.10.23289790. [ Link] [ DOI] 9. Mohammed IJ, Sarhat ER, MAH, Sarhat TR. Assessment of salivary Interleukin (IL)-6, IL-10, Oxidative Stress, Antioxidant Status, pH, and Flow Rate in Dental Caries Experience patients in Tikrit Province. SRP. 2021;12(1):55-59. https://dx.doi.org/10.31838/srp.2021.1.10. [ Link] [ DOI] 10. Nejatian Hoseinpour A, Bassami M, Ahmadizad S, Donath L, Setayesh S, Mirzaei M, et al. The influence of resistance training on inflammatory markers, body composition and functional capacity in healthy older adults: A systematic review and meta-analysis. Arch Gerontol Geriatr. 2025 Mar;130:105731. https://doi.org/10.1016/j.archger.2024.105731. [ DOI] [ PubMed] 11. Docherty S, Harley R, McAuley JJ, Crowe LAN, Pedret C, Kirwan PD, et al. The effect of exercise on cytokines: implications for musculoskeletal health: a narrative review. BMC Sports Sci Med Rehabil. 2022 Jan;14(1):5. https://doi.org/10.1186/s13102-022-00397-2. [ DOI] [ PubMed] 12. Shobeiri P, Seyedmirzaei H, Karimi N, Rashidi F, Teixeira AL, Brand S, et al. IL-6 and TNF-α responses to acute and regular exercise in adult individuals with multiple sclerosis (MS): a systematic review and meta-analysis. Eur J Med Res. 2022 Sep;27(1):185. https://doi.org/10.1186/s40001-022-00814-9. [ DOI] [ PubMed] 13. Khalafi M, Akbari A, Symonds ME, Pourvaghar MJ, Rosenkranz SK, Tabari E. Influence of different modes of exercise training on inflammatory markers in older adults with and without chronic diseases: A systematic review and meta-analysis. Cytokine. 2023 Sep;169:156303. https://doi.org/10.1016/j.cyto.2023.156303. [ DOI] [ PubMed] 14. Silva FM, Duarte-Mendes P, Teixeira AM, Soares CM, Ferreira JP. The effects of combined exercise training on glucose metabolism and inflammatory markers in sedentary adults: a systematic review and meta-analysis. Sci Rep. 2024 Jan;14(1):1936. https://doi.org/10.1038/s41598-024-51832-y. [ DOI] [ PubMed] 15. Irandoust K, Hamzehloo A, Youzbashi L, Taheri M, Ben Saad H. High intensity interval training and L-Arginine supplementation decrease interleukin-6 levels in adult trained males. Tunis Med. 2022 Oct;100(10):696-705. [ PubMed] 16. Baião D, Conte Jr C, Silva J, Paschoalin V, Alvares T. L-Arginine Supplementation and Nitric Oxide Production:No Additional Effect When Associated to Exercise. Food and Nutrition Sciences. 2013;4(8):779-84. http://dx.doi.org/10.4236/fns.2013.48101. [ Link] [ DOI] 17. Nascimento MAD, Lira FDS, Punaro GR, Mello MT, Tufik S, Higa EMS. Short-term l-arginine supplementation attenuates elevation of interleukin 6 level after resistance exercise in overweight men. Clinical Nutrition ESPEN. 2017;22:43-47. https://doi.org/10.1016/j.clnesp.2017.09.001. [ Link] [ DOI] 18. Irandoust K, Ben Saad H, Mohammadgholiha F, Taheri M, Dergaa I. Effects of dry cupping therapy and creatine supplementation on inflammatory and cardiovascular responses to the Wingate test in handball players. Tunis Med. 2022 Mar;100(3):262-69. [ PubMed] 19. Khodabakhsh Nokola M, Gholami M, Abednatanzi H. The Effect of 12 Weeks Endurance Training with L-arginine Supplementation on the Levels of IL-6 and TNF-α in Menopausal Women with Hypertension. J North Khorasan Univ Med Sci. 2021;13(2):61-69. http://dx.doi.org/10.29252/nkjmd-09024. [ Link] [ DOI] 20. Barcelos GT, Rossato DD, Perini JL, Pinheiro LP, Carvalho C, Jaenisch RB, et al. Effects of l-arginine supplementation associated with continuous or interval aerobic training on chronic heart failure rats. Metabolism. 2017 Nov;76:1-10. https://doi.org/10.1016/j.metabol.2017.06.009. [ DOI] [ PubMed] 21. Cullen T, Thomas AW, Webb R, Hughes MG. Interleukin-6 and associated cytokine responses to an acute bout of high-intensity interval exercise: the effect of exercise intensity and volume. Appl Physiol Nutr Metab. 2016 Aug;41(8):803-808. https://doi.org/10.1139/apnm-2015-0640. [ DOI] [ PubMed] 22. Kurhaluk N, Tkaczenko H. L-Arginine and Nitric Oxide in Vascular Regulation-Experimental Findings in the Context of Blood Donation. Nutrients. 2025 Feb;17(4):665. https://doi.org/10.3390/nu17040665. [ DOI] [ PubMed] 23. Dorneles GP, Haddad DO, Fagundes VO, Vargas BK, Kloecker A, Romão PR, et al. High intensity interval exercise decreases IL-8 and enhances the immunomodulatory cytokine interleukin-10 in lean and overweight-obese individuals. Cytokine. 2016 Jan;77:1-9. https://doi.org/10.1016/j.cyto.2015.10.003. [ DOI] [ PubMed] 24. Mohammadnia Ahmadi M, Najarian E, Nezamdoost Z, Sadeghi-Tabas S, Abtahi Eivary SH. Effects of Supramaximal Intensity Interval Training on Resistin and Cardiometabolic Health Indices in Overweight Nonpostmenopausal Women. Sports Health. 2025 Nov;17(6):1140-48. https://doi.org/10.1177/19417381251315059. [ DOI] [ PubMed] 25. Martina V, Masha A, Gigliardi VR, Brocato L, Manzato E, Berchio A, et al. Long-term N-acetylcysteine and L-arginine administration reduces endothelial activation and systolic blood pressure in hypertensive patients with type 2 diabetes. Diabetes Care. 2008 May;31(5):940-44. https://doi.org/10.2337/dc07-2251. [ DOI] [ PubMed] 26. Pedersen BK. The anti-inflammatory effect of exercise: its role in diabetes and cardiovascular disease control. Essays Biochem. 2006;42:105-17. https://doi.org/10.1042/bse0420105. [ DOI] [ PubMed] 27. Atakan MM, Koşar ŞN, Güzel Y, Tin HT, Yan X. The Role of Exercise, Diet, and Cytokines in Preventing Obesity and Improving Adipose Tissue. Nutrients. 2021 Apr;13(5):1459. https://doi.org/10.3390/nu13051459. [ DOI] [ PubMed] 28. Ren Y, Zhao H, Yin C, Lan X, Wu L, Du X, et al. Adipokines, Hepatokines and Myokines: Focus on Their Role and Molecular Mechanisms in Adipose Tissue Inflammation. Front Endocrinol (Lausanne). 2022 Jul;13:873699. https://doi.org/10.3389/fendo.2022.873699. [ DOI] [ PubMed] 29. Gram DY, Şentürk M, Kamacı Özocak G, Doğan ND, Ekebaş G, Atasever A, et al. Effect of dietary L-arginine supplementation on the expression of vascular endothelial growth factor A, its receptors, and nitric oxide system components in the pancreas of streptozotocin-induced diabetic rats. Tissue Cell. 2025 Dec;97:103072. https://doi.org/10.1016/j.tice.2025.103072. [ DOI] [ PubMed] 30. Rath M, Müller I, Kropf P, Closs EI, Munder M. Metabolism via Arginase or Nitric Oxide Synthase: Two Competing Arginine Pathways in Macrophages. Front Immunol. 2014 Oct;5:532. https://doi.org/10.3389/fimmu.2014.00532. [ DOI] [ PubMed] 31. Dyakova EY, Kapilevich LV, Shylko VG, Popov SV, Anfinogenova Y. Physical exercise associated with NO production: signaling pathways and significance in health and disease. Front Cell Dev Biol. 2015 Apr;3:19. https://doi.org/10.3389/fcell.2015.00019. [ DOI] [ PubMed] 32. Lira VA, Brown DL, Lira AK, Kavazis AN, Soltow QA, Zeanah EH, et al. Nitric oxide and AMPK cooperatively regulate PGC-1 in skeletal muscle cells. J Physiol. 2010 Sep;588(Pt 18):3551-66. https://doi.org/10.1113/jphysiol.2010.194035. [ DOI] [ PubMed] 33. Fateh HL, Najafabadi MS, Moludi J, Ahmed DH, Rahman HS, Tawfeeq HM. The role of L-Arginine in improvement of lipid profile, liver enzymes, and blood pressure: A systematic review of randomized control trial studies. Human Nutrition & Metabolism. 2025;41:200310. https://doi.org/10.1016/j.hnm.2025.200310. [ Link] [ DOI] 34. Abassi W, Ouerghi N, Hammami MB, Jebabli N, Feki M, Bouassida A, et al. High-Intensity Interval Training Reduces Liver Enzyme Levels and Improves MASLD-Related Biomarkers in Overweight/Obese Girls. Nutrients. 2025 Jan;17(1):164. https://doi.org/10.3390/nu17010164. [ DOI] [ PubMed] 35. Liang M, Wang Z, Li H, Cai L, Pan J, He H, et al. L-Arginine induces antioxidant response to prevent oxidative stress via stimulation of glutathione synthesis and activation of Nrf2 pathway. Food Chem Toxicol. 2018 May;115:315-28. https://doi.org/10.1016/j.fct.2018.03.029. [ DOI] [ PubMed] 36. Bishop DJ, Botella J, Genders AJ, Lee MJ, Saner NJ, Kuang J, et al. High-Intensity Exercise and Mitochondrial Biogenesis: Current Controversies and Future Research Directions. Physiology (Bethesda). 2019 Jan;34(1):56-70. https://doi.org/10.1152/physiol.00038.2018. [ DOI] [ PubMed] |
